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DMT (N, N-Dimethyltryptamine) is a naturally occurring tryptamine that is extracted from several types of plants and animals. DMT is the active compound of ayahuasca, a brew made out of Banisteriopsis caapi and other plants such as Psychotria Viridis (chacruna), Diplopterys cabrerana (chaliponga or chacropanga), and Mimosa tenuiflora, among other DMT containing plants.
Also, DMT can be smoked/vaporized or taken orally. When used orally it is inactive in the absence of a Monoamine Oxidase (MAO) inhibitor. When taken orally in conjunction with an MAO inhibitor, it is known as Ayahuasca or Yage.
The psychedelic and hallucinogenic effects of DMT are caused by complicated changes in the brain. DMT acts as a partial agonist of serotonin (5-HT) receptors, mainly the 1A, 2A, and 2C receptor subtypes. The 5-HT2A receptor is believed to be the primary target of classic serotonergic-mediated psychedelic compounds, although 5-HT1A and 5-HT2C receptors may play a role in the effects of DMT (Carbonaro & Gatch, 2016). DMT is a functional and structural analog of other psychedelic compounds such as 5-MeO-DMT, 5-OH-DMT, psilocybin (4-PO-DMT), and O-Acetylpsilocin (4-AcO-DMT).
Pure DMT is a clear or white crystal or solid, whereas DMT that is not pure may look yellow, brown, orange, or pink depending on the method of preparation. DMT can look like snowflakes, powder, or be waxy, and has been described as smelling like burnt rubber or new shoes.
In its natural state, DMT preparations may look like a brownish/green herbal mixture or a brownish/red liquid when made into Ayahuasca tea.
Under prohibition and in the illicit market, there is no guarantee of a safe dose because you may not know the content or potency of a substance. Everyone reacts differently to DMT, and because of the vivid hallucinations associated with the drug, it is extremely important to have a sober “sitter” present who you can trust.
DMT can be consumed as tea (ayahuasca), but the most common way to consume DMT is to smoke/vaporize it. When smoked/vaporized, the onset is quick and the effects are intense and short-lived.
A “standard” vaporized DMT dosage may look like the following (Erowid, n.d.):
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Threshold 2 – 5 mg
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Light 10 – 20 mg
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Medium 20 – 40 mg
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High 40 – 60 mg
Typically, the onset is 15 – 60 seconds, the duration of the high is 5 – 20 minutes, and the afterglow lasts 15 – 60 minutes.
A DMT HIGH USUALLY RESULTS IN (TACKETT, 2018):
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Altered perception of time and space.
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Feelings of intense joy.
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Visual and auditory hallucinations.
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Out-of-body experience.
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Perception of bright, intensified colors.
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Perceived insights or epiphanies (often believed to have come from aliens, divinities, or other mystical beings).
Some of the most common side-effects of DMT are elevated blood pressure and heart rate, which means that people suffering from any kind of cardiovascular disease should take serious precautions when taking DMT. Other side effects include dizziness, nausea, and lack of coordination. Ayahuasca may cause vomiting and diarrhea. Avoid driving a vehicle or using heavy machinery either while or immediately after the use of DMT.
DANGEROUS OR POTENTIALLY FATAL INTERACTIONS (THE THIRD WAVE, N.D.):
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Combination with lithium. Lithium is sometimes prescribed for bipolar and other mood disorders. DMT should never be taken by anyone who also taking Lithium. This combination has resulted in extremely dangerous psychological distress, including complete loss of contact with reality, psychotic symptoms and behavior, mania and delirium, and most concerning, seizures.
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DMT should not be taken in combination with SSRIs, high blood pressure drugs, appetite suppressants, medicine for breathing problems, central nervous system depressants, vasodilators, antipsychotic drugs, barbiturates, and alcohol.
DMT, and in particular Ayahuasca, has shown potential for the treatment of several mental health issues such as addiction, eating disorders, and depression, among others (Labate et al., 2013). Anecdotal reports suggest that greater self-awareness and spiritual connection to the world can be gained from properly using DMT (The Third Wave, n.d.).
DMT has been used historically and is still used by many groups for ritual and healing purposes. The northwestern region of the Amazon Basin, where DMT exists in nature. Hosts the largest population of people that use DMT-containing substances for ritualistic healing. Many indigenous groups in Colombia, Peru, Ecuador, and Brazil use some variant of DMT it their traditional medicines (The Conversation, 2016). Buy DMT Crystal Online Colorado
WHEN USING DMT KEEP IN MIND:
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Start low and go slow. You cannot judge content or purity by appearance, and DMT amounts can vary within each batch
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DMT causes vivid hallucinations so it is extremely important to have a sober “sitter” present who you know and trust and use in a safe and relaxing environment
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Individuals with a personal or family history of any psychotic disorder or nonpsychotic mania should avoid taking any psychedelic compounds, including DMT.
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Do not combine DMT with Lithium or SSRIs
WHEN SMOKING DMT:
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DMT smoke/vapor is harsh on the lungs, so use pipes with cooling chambers and do not hold in smoke – holding in smoke will not make you higher
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Clean and pre-warm pipes if they have been used before to avoid accidentally inhaling DMT or other substances from a previous session
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Use glass or metal pipes when possible to avoid fumes that may come from wood or plastic
COMBINATIONS
For the purposes of harm reduction, it is not advisable to combine substances. A combination of substances will not necessarily produce an equal mixing of effects. And is essentially a novel drug in its own right. Oftentimes combinations are not merely additive but produce “synergy”, where the effects are multiplied or exponential. There are some substances that should never be combined because they may produce toxic or potentially fatal effects. This should be taken into account if you choose to combine substances. So start with lower doses of each substance than you would usually take if taken alone.
DMT is classified as Schedule III substances in Canada under the Controlled Drugs and Substances Act of 1996 (Controlled Drugs and Substances Act, 1996). Possession, production, and trafficking of Schedule III substances are punishable by law.
